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P01 – Coalminer: a parallel processing and user-customizable tool for GFF3 to JSON translation
Miralto M1, AmbrosinoL1, Colantuono C1, Sangiovanni M1, Chiusano ML1,2
1Research Infrastructures for Marine biological resources department, Stazione Zoologica “Anton Dohrn”, Napoli
2Department of Agriculture, University of Naples Federico II, Portici, Italy
P02 – VarGenius2 finds SNVs and CNVs in WES, WGS and RNASeq and paves the way to implementation of downstream algorithms for cohort data traversing
Varavallo A1, Musacchia F1, Castello L1, Torella A1, Banfi S1, Nigro V1,2, Casari G1
1Telethon Institute for Genetics and Medicine, Viale Campi Flegrei, 34, 80078, Pozzuoli (Naples), Italy
2Università degli studi della Campania ‘Luigi Vanvitelli’, Caserta, Italy

P03 – Weighted protein network analysis (WPCNA) decrypt Rab8b and Rab31 as key affiliates of exosomal secretion; extending their role in Parkinson’s disease pathology seeding and spreading
Kumar R1,2,3, Donakonda S4, Müller SA1, Lichtenthaler SF1,6, Höglinger GU2,5, Kögelsperger T1,3
1German Center for Neurodegenerative Diseases e.V. (DZNE), Dept. for Translational Neurodegeneration, Munich, Germany
2Klinikum rechts der Isar der Technischen Universität München, Germany
3Neurologische Klinik und Poliklinik, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany
4Institute of Immunology and Experimental Oncology Technischen Universität München, Germany
5Department of Neurology, Hannover Medical School (MHH), Hannover, Germany
6Neuroproteomics, Institute for Advanced Study, Technical University of Munich, Munich, Germany.

P04 – Bringing radiomics into a multi-omics framework for a comprehensive genotype–phenotype characterization of oncological diseases
Zanfardino M1, Franzese M1, Pane K1, Cavaliere C1, Monti S1, Esposito G2, Salvatore M1, Aiello M1
1IRCCS SDN, Naples, Italy
2Bio Check Up S.r.l., Naples 80121, Italy

P05 – ROBIN: an R package for validation of community robustness
Policastro V1, Righelli D1, Cutillo L2, De Feis I1, Carissimo A1
1Istituto per le Applicazioni del Calcolo ‘Mauro Picone’, CNR, Naples, Italy
2The School of Mathematics, University of Leeds, United Kingdom

P06 – The Empusa code generator and its application to GBOL, an extendable ontology for genome annotation
Koehorst JJ1, Schaap PJ1, van Dam JCJ1, Vik JO2, Martins dos Santos VAP1, Suarez-Diez M1
1Wageningen University & Research, Wageningen, The Netherlands
2Centre for Integrative Genetics (CIGENE), Norwegian University of Life Sciences, Norway

P07 – ARPIR: Automatic RNA-Seq Pipelines with Interactive Report
Spinozzi G1, Tini V1, Adorni A1, Falini B1, Martelli MP1
1Department of Medicine, Section of Hematology, University of Perugia, Perugia, Italy

P08 – Jig of Life: An Uncertainty Analysis of Bayesian Network for sc-RNA seq
Li S1
1University of Leeds, United Kingdom
P09 – Assessment of Crohn’s Disease Genetic Variants and Risk Factors in an Inflammatory Bowel Disease Patient Population
Dago ND1,2, Pinelli M1, Giacomelli M1, Zunica F1, Tripodi SI1, Badolato R1, GENMICI study group.
1Department of Pediatric, Institut of Molecular Medecine Angelo Nocivelli, University of Brescia, Italy
2Department of Genetic and Biochemistry, Peleforo Gon Coulibaly University of Korhogo, Ivory Coast.
P10 – EnsMAP-DP – novel probabilistic method for clustering scRNAseq data
Krzak M1, Raykov Y2, Boukouvalas A3, Cutillo L4, Angelini C1
1Institute for Applied Mathematics ‘Mauro Picone’, Naples, Italy
2Aston University, Birmingham, United Kingdom
3Prowler.io, Cambridge, United Kingdom
4School of Mathematics, University of Leeds, United Kingdom
P11 – Disclosing the key biological target of Crellastatin A through a combination of proteomic approaches
Morretta E1,2, Di Mauro M1, Festa C3, Mozzicafreddo M4, Tosco A1, Monti MC1, Casapullo A1
1Department of Pharmacy, University of Salerno, Fisciano, Italy
2PhD Program in Drug Discovery and Development, Dipartimento di Farmacia, University of Salerno, Fisciano, Italy
3Department of Pharmacy, University of Naples ‘Federico II’, Naples, Italy
4School of Biosciences and Veterinary Medicine, University of Camerino, Italy
P12 – Carbamoyl-phosphate synthase 1, the missing piece in Phomoxanthone A induced apoptosis
Ceccacci S1, Morretta E1, Stork B2, Proksch P3, Monti MC1
1Department of Pharmacy, University of Salerno, Fisciano, Italy
2Heinrich-Heine-Universität, Molecular Medicine I, Düsseldorf, Germany
3Heinrich-Heine-Universität, Pharmaceutical Biology and Biotechnology, Düsseldorf, Germany
P13 – Toward Integrating Machine Learning and Modeling in Translational and Community Analysis of Interactomic Regulation Networks
Liberati D1
1National Research Council, Milano, Italy
P14 – Bioinformatics applications for the study of molecular mechanisms and metabolic networks in oncological diseases
Dotolo S1,2, Facchiano A2, Forootani A1, Marabotti A3, Ritrovato P4, Troiano L5, Tagliaferri R1
1NeuRoNe Lab, Department of Business Sciences, Management & Innovation Systems (DISA-MIS), University of Salerno, Italy.
2Institute of Food Science (ISA-CNR), Avellino (Italy)
3Department of Chemistry and Biology “A. Zambelli” (DCB), University of Salerno, Italy
4Department of Computer and Electrical Engineering and Applied Mathematics (DIEM), University of Salerno, Italy
5Department of Engineering, University of Sannio, Benevento, Italy.
P15 – In-Silico Construction of Homo Sapiens Antimicrobial and Immunemodulatory Peptide (AMP) Database
Kumar A1, Csosz E1
1Proteomics Core Facility, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
P16 – HaDeX: an R package and web-server for analysis of data from hydrogen-deuterium exchange mass spectrometry experiments
Burdukiewicz M1, Puchała W2, Dabrowska KA2, Cysewski D2, Dadlez M2
1Faculty of Mathematics and Information Science, Warsaw University of Technology, Poland
2Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland
P17 – Genomic analysis of the PIWIL1-piRNA pathway in colorectal cancer cell lines: exploiting various bioinformatic tools and smallRNA databases for a precise analysis of piRNA
Geles K1,2, Sellitto A1, D’Agostino Y1, Weisz A1,2,3, Giurato G1,2, Rizzo F1,2
1Laboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry ‘Scuola Medica Salernitana’, University of Salerno, Baronissi (SA), Italy
2Genomix4Life srl, Baronissi (SA), Italy
3Medical Genomics Program, Department of Onco‐Haematology ̔ ‘SS. Giovanni di Dio e Ruggi d’Aragona ̓ University Hospital, University of Salerno, Salerno, Italy
P18 – A dockerized solution for somatic variants detection in patients affected by Clonal Hematopoiesis of Indeterminate Potential
Palumbo D1, Giurato G2, Rizzo F2, Weisz A2
1Casa di Cura Montevergine, Mercogliano, Italy.
1Laboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi, Italy
P19 – MotoCell, a web application for quantitative study of cell movement
Tufano R1, Sepe L2, Toscano E1, Boccia A2, Paolella G1,2
1Department of Molecular Medicine and Medical Biotechnology, Naples, Italy
1CEINGE Advanced Biotechnologies, Naples, Italy
P20 – Analysis of NGS data for the identification of mutations involved in the pathogenesis of rare tumors
Memoli D1, Tarallo R1, Giurato G1, Weisz A1
1Laboratory of Molecular Medicine and Genomics, Department of Medicine, Surgery and Dentistry ‘Scuola Medica Salernitana’, University of Salerno, Baronissi, Italy
P21 – Comparison of members of the TGase enzyme family: insight the structure&function relationships
Giordano D1, Facchiano A1
1Istituto di Scienze dell’Alimentazione, CNR, Avellino, Italy
P22 – Metagenomics pipeline for detection of biological entities from shotgun sequencing: a novel and cost effective approach
Ferravante C1, Di Loria A1, Ciaramella P1, Weisz2, Giurato G2
1Dep. of Veterinary Medicine and Animal Production – University of Naples Federico II, Naples, Italy
2Laboratory of Molecular Medicine and Genomics – Dep. of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi, Italy
P23 – Benchmarking of methods for predicting protein stability
Marabotti A1, Del Prete E2, Scafuri B1,3, Facchiano A3
1Dept. Chemistry and Biology ‘A. Zambelli’, University of Salerno, Fisciano, Italy;
2CNR-IAC, National Research Council, Institute for Calculus Applications “Mauro Picone”, Naples, Italy
3CNR-ISA, National Research Council, Institute of Food Science, Avellino, Italy
P24 – Serum degradation analysis by MALDI/ToF: a new method and tool
Romano P1, Beitia M2, Profumo A1
1IRCCS Ospedale Policlinico San Martino, Genoa, Italy
2University of the Basque Country (UPV/EHU), Leioa, Biscay, Spain
P25 – A reproducible research tool: the R6 Class easyReporting
Righelli D1, Angelini C1
1Istituto per le Applicazioni del Calcolo “M. Picone” – CNR, Naples, Italy
P26 – A non-Markovian stochastic model for the accumulation of genetic mutations
Meoli A1, Beerenwinkel N2 Lebid M2
1Dipartimento di Matematica, Università degli Studi di Salerno, Fisciano (SA), Italy
2Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland
P27 – From Information Retrieval Benchmarking to Precision Medicine Knowledge Discovery
Rybinski M1, Karimi S1, Paris C1
1Data61, CSIRO, Australia
P28 – Tools integration for a large-scale searching of potential ligands of a protein target
Biancaniello C1, Argenio MA1, Dotolo S1, Facchiano A1
1CNR-ISA, Avellino, Italy
P29 – Proteomics Approaches to the study of Post-Translational Modifications: the case of Paraoxonase 2 (PON2)
Carusone TM1, Porzio E1, Cardiero G2, Lacerra G2, Manco G1
1CNR-IBBC, Naples, Italy
2CNR-IGB, Naples, Italy
P30 – The European Bioinformatics Community (EuBIC): who are we and what do we do?
Locard-Paulet M1
1University of Copenhagen, Denmark

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