{"id":1202,"date":"2015-05-05T13:00:34","date_gmt":"2015-05-05T13:00:34","guid":{"rendered":"http:\/\/www.igst.it\/nettab\/2015\/?page_id=1202"},"modified":"2015-10-06T15:30:12","modified_gmt":"2015-10-06T15:30:12","slug":"dursi-tutorial","status":"publish","type":"page","link":"http:\/\/www.igst.it\/nettab\/2015\/programme\/tutorials\/dursi-tutorial\/","title":{"rendered":"Pasqualina D’Ursi Tutorial"},"content":{"rendered":"
<\/a><\/b><\/div>\n\n\n\n\n\n
\n
\nTutorial B
\nStructural Bionformatics in Drug Discovery<\/strong> (sponsored by InterOmics)
\nTuesday October 13, 2015, 10:00 – 13:00
\n
The tutorial focuses on applications of fast and inexpensive docking protocols combined with accurate, but more expensive, molecular dynamics techniques to predict more reliable protein-ligand complexes. Molecular dynamics can be used during the preparation of the protein before docking and for the refinement of docked complex considering the protein flexibility.<\/p>\n

This tutorial will present a case study, development of new procedures for the identification of CFTR (Cystic fibrosis transmembrane conductance regulator) drugs: a multidisciplinary approach using real time surface plasmon resonance interaction assays supported by bioinformatics strategies on HPC infrastructure.\n<\/p><\/div>\n

 <\/td>\n<\/tr>\n
<\/td>\n\nPasqualina D’Ursi<\/a><\/b>,
\nInstitute of Biomedical Technologies (ITB), National Research Council, Milano, Italy<\/td>\n<\/tr>\n
\n
\nPasqualina D’Ursi is a Senior Researcher at the Institute of Biomedical Technologies (ITB) of the Italian National Research Council. She received a BS Degree in Biological Science and a PhD in Molecular Medicine at University of Milan and Specialization in Pharmacological Research at “Mario Negri” Institute, Milan, Italy.<\/p>\n

Her research interests involve modelling, drug design and computational study of the impact of environmental pollutants on human health. She is involved in the following projects: molecular mechanisms of HIV-1 matrix protein p17 variants in promoting tumorigenesis and neurodegeneration, development and application of modeling techniques in the fields of protein-ligand interactions for the rational drug design of Cystic Fibrosis therapy, phosphodiesterase (PDE) and viral protein.\n<\/p><\/div>\n<\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Tutorial B Structural Bionformatics in Drug Discovery (sponsored by InterOmics) Tuesday October 13, 2015, 10:00 – 13:00 The tutorial focuses on applications of fast and inexpensive docking protocols combined with accurate, but more expensive, molecular dynamics techniques to predict more reliable protein-ligand complexes. Molecular dynamics can be used during the preparation of the protein before […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":83,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-1202","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/pages\/1202","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/comments?post=1202"}],"version-history":[{"count":14,"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/pages\/1202\/revisions"}],"predecessor-version":[{"id":1726,"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/pages\/1202\/revisions\/1726"}],"up":[{"embeddable":true,"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/pages\/83"}],"wp:attachment":[{"href":"http:\/\/www.igst.it\/nettab\/2015\/wp-json\/wp\/v2\/media?parent=1202"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}